Recombinant mouse gamma-Synuclein protein
Sncg, also known as gamma-Synuclein, is an acidic neuronal protein. It plays a role in neurofilament network integrity. This protein activates the MAPK and Elk-1 signal transduction pathway. According to some research, Sncg may play an important role in invasion, infiltration and apoptosis of esophageal cancer and serve as target spots in the targeted therapy of esophageal cancer. Recombinant mouse Sncg, fused to His-tag at N-termineus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Gamma-synuclein, C79089, persyn, Uscropmag-synuclein, C79089, 2, SNCG
Expression System
E.coli
Antigen Species
Mouse
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by absorbance at 280 nm)
Purity
> 95% by SDS-PAGE
Molecular Weight
15.5 kDa (146aa) Confirmed by MALDI-TOF
Additionnal Information
References & Citations
Ji H., et al. (1997) Cancer Res. 57 (4) :759-64.; ; Luo JH, et al. (2013) Asian Pac J Trop Med. 6 (7) :516-9.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl
Scientific Category
Neuroscience
NCBI Accession Number
NP_035560
Uniprot Accession Number
Q9Z0F7
Species
Mouse
AA Sequence
MDVFKKG FSIAKEGVVG AVEKTKQGVT EAAEKTKEGV MYVGTKTKEN VVQSVTSVAE KTKEQANAVS AVVSSVNTV ANKTVEEAEN IVVTTGVVRK EDLEPPAQDQ EAKEQEENEE AKSGED
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