Recombinant human CD16b/FCGR3B protein

FCGR3B, also known as low affinity immunoglobulin gamma Fc region receptor III-B isoform 2, is a member of Ig super family. It encodes a glycosylphosphatidylinositol (GPI) -anchored protein that is expressed constitutively by neutrophils and after gamma-interferon stimulation by eosinophils. This protein binds to complex or aggregated IgG and monomeric IgG. Unlike III-A, it cannot mediate antibody-dependent cytotoxicity and phagocytosis. It can be a trap of immune complexes in peripheral blood circulation that does not activate neutrophils. Recombinant human FCGR3B, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Low affinity immunoglobulin gamma Fc region receptor III-B isoform 2, IgG Fc receptor III-1, IGFR3, FCRIIIb, FCRIII, FCR-10, FCGR3B, FCGR3, FcgammaRIIIb, Fc-gamma RIII-beta, FCG3, Fc gamma receptor IIIb, Fc fragment of IgG receptor IIIb, CD16-I, CD16b, CD16

Expression System

Baculovirus

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Molecular Weight

21.4 kDa (188aa)

Additionnal Information

Fc g RIIIB, CD16b, Low affinity immunoglobulin gamma Fc region receptor III-B isoform 2, FCGR3B, CD16, CD16b, FCG3, FCGR3, FCR-10, FCRIII, FCRIIIb, ATGP3673-10 µg, ATGP3673-20 µg, ATGP3673-50 µg, ATGP3673-100 µg, ATGP3673-250 µg, ATGP3673-500 µg, ATGP3673-1 mg, ATGP3673-10, ATGP3673-20, ATGP3673-50, ATGP3673-100, ATGP3673-250, ATGP3673-500, ATGP3673-1