Recombinant human CD81 protein

CD81, also known as CD81 antigen isoform 1, belongs to the tetraspanin family. It interacts directly with immunoglobulin superfamily member 8 (IGSF8, CD316) and CD36. In B cells, it is part of a complex with CD21, CD19 and Leu13. This complex reduces the threshold for B cell activation through B cell receptors by linking Ag specific recognition and CD21 mediator recognition. On T cells it associates with CD4 and CD8 and provides a costimulatory signal with CD3. Recombinant human CD81, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

CD81 antigen isoform 1, CD81, CVID6, S5.7, TAPA1, TSPAN28

Expression System

Baculovirus

Antigen Species

Human

Tag

HIgG-His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 95% by SDS-PAGE

Molecular Weight

37 kDa (331aa)

Additionnal Information

CD81, CD81 antigen isoform 1, CD81, CVID6, S5.7, TAPA1, TSPAN28, ATGP3661-10 µg, ATGP3661-20 µg, ATGP3661-50 µg, ATGP3661-100 µg, ATGP3661-250 µg, ATGP3661-500 µg, ATGP3661-1 mg, ATGP3661-10, ATGP3661-20, ATGP3661-50, ATGP3661-100, ATGP3661-250, ATGP3661-500, ATGP3661-1