What is the catalog number for Recombinant human ULBP-4/RAET1E protein?

The catalog number for Recombinant human ULBP-4/RAET1E protein is ATGP3656-050.

What sizes are available for Recombinant human ULBP-4/RAET1E protein?

Recombinant human ULBP-4/RAET1E protein is available in the following size(s): 50 µg.

Is Recombinant human ULBP-4/RAET1E protein in stock?

Recombinant human ULBP-4/RAET1E protein is currently made to order / not held in immediate stock. Contact us for lead time.

Recombinant human ULBP-4/RAET1E protein

RAET1E, also known as NKG2D ligand 4 isoform 1, is a member of the RAET1/ULBP family of cell surface protein that function as ligands for NKG2D. This protein is abnormally expressed on most colon cancer and some other tumor cell lines and virus infected peripheral blood cells. It binds and co-stimulates NKG2D expressing effector cells including NK cells, NKT cells, gamma delta T cells, and CD8+ alpha beta T cells, activating cytolytic activity and/or cytokine production. Also, it functions as a stress-induced ligand for NKG2D receptor. Recombinant human RAET1E, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Retinoic acid early transcript 1E, Lymphocyte effector toxicity activation ligand, NKG2D ligand 4, N2DL-4, NKG2DL4, RAE-1-like transcript 4, UL16-binding protein 4, LETAL, N2DL4, ULBP4

Expression System

Baculovirus

Antigen Species

Human

Tag

HIgG-His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 85% by SDS-PAGE

Molecular Weight

49.6 kDa (437aa)

Additionnal Information

ULBP4, RAET1E, NKG2D ligand 4 isoform 1, RAET1E, bA350J20.7, LETAL, N2DL-4, NKG2DL4, RAET1E2, RL-4, ULBP4, ATGP3656-10 µg, ATGP3656-20 µg, ATGP3656-50 µg, ATGP3656-100 µg, ATGP3656-250 µg, ATGP3656-500 µg, ATGP3656-1 mg, ATGP3656-10, ATGP3656-20, ATGP3656-50, ATGP3656-100, ATGP3656-250, ATGP3656-500, ATGP3656-1

References & Citations

Chalupny NJ., et al, (2003) Biochem. Biophys. Res. Commun. 305:129-135.; ; Kong Y., et al, (2009) Blood 114:310-317.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Scientific Category

Immunology

NCBI Accession Number

NP_631904

Uniprot Accession Number

Q8TD07

Species

Human

N Terminal Sequence

Ala

AA Sequence

ADPHSLCFNF TIKSLSRPGQ PWCEAQVFLN KNLFLQYNSD NNMVKPLGLL GKKVYATSTW GELTQTLGEV GRDLRMLLCD IKPQIKTSDP STLQVEMFCQ REAERCTGAS WQFATNGEKS LLFDAMNMTW TVINHEASKI KETWKKDRGL EKYFRKLSKG DCDHWLREFL GHWEAMPEPT VSPVNASDIH WSSSSLPDVE PKSCDKTHTC PPCPAPELLG GPSVFLFPPK PKDTLMISRT PEVTCVVVDV SHEDPEVKFN WYVDGVEVHN AKTKPREEQY NSTYRVVSVL TVLHQDWLNG KEYKCKVSNK ALPAPIEKTI SKAKGQPREP QVYTLPPSRD ELTKNQVSLT CLVKGFYPSD IAVEWESNGQ PENNYKTTPP VLDSDGSFFL YSKLTVDKSR WQQGNVFSCS VMHEALHNHY TQKSLSLSPG KHHHHHH