Recombinant human CD158k/KIR3DL2 protein

KIR3DL2, also known as killer cell immunoglobulin-like receptor 3DL2 isoform 1, is a type 1 transmembrane protein of the p70 family of killer cell Ig-like receptors. Killer cell immunoglobulin-like receptors (KIRs) are expressed by natural killer cells and subsets of T cells. The KIRs are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. Also, these proteins are thought to play an important role in regulation of the immune response. Recombinant human KIR3DL2, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Killer cell immunoglobulin-like receptor 3DL2 isoform 1, Killer cell immunoglobulin like receptor three Ig domains and long cytoplasmic tail 2, CD158 antigen-like family member K, Natural killer-associated transcript 4, NKAT-4, p70 natural killer cell receptor clone CL-5, p70 NK receptor CL-5, nkat4a, nkat4b, CD158K

Expression System

Baculovirus

Antigen Species

Human

Tag

HIgG-His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 85% by SDS-PAGE

Molecular Weight

62.2 kDa (561aa)

Additionnal Information

KIR3DL2, CD158k, Killer cell immunoglobulin-like receptor 3DL2 isoform 1, KIR3DL2, 3DL2, CD158K, KIR-3DL2, NKAT-4, NKAT4, NKAT4B, p140, ATGP3649-10 µg, ATGP3649-20 µg, ATGP3649-50 µg, ATGP3649-100 µg, ATGP3649-250 µg, ATGP3649-500 µg, ATGP3649-1 mg, ATGP3649-10, ATGP3649-20, ATGP3649-50, ATGP3649-100, ATGP3649-250, ATGP3649-500, ATGP3649-1

References & Citations

Dohring C., et al, (1996) J. Immunol. 156:3098-3101.; ; Pende D., et al, (1996) J. Exp. Med. 184:505-518.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Scientific Category

Immunology

NCBI Accession Number

NP_006728

Uniprot Accession Number

P43630

Species

Human

N Terminal Sequence

Ala

AA Sequence

LMGGQDK PFLSARPSTV VPRGGHVALQ CHYRRGFNNF MLYKEDRSHV PIFHGRIFQE SFIMGPVTPA HAGTYRCRGS RPHSLTGWSA PSNPLVIMVT GNHRKPSLLA HPGPLLKSGE TVILQCWSDV MFEHFFLHRE GISEDPSRLV GQIHDGVSKA NFSIGPLMPV LAGTYRCYGS VPHSPYQLSA PSDPLDIVIT GLYEKPSLSA QPGPTVQAGE NVTLSCSSWS SYDIYHLSRE GEAHERRLRA VPKVNRTFQA DFPLGPATHG GTYRCFGSFR ALPCVWSNSS DPLLVSVTGN PSSSWPSPTE PSSKSGICRH LH