Recombinant human IL-13R alpha 2/IL13RA2 protein
IL13RA2, also known as interleukin-13 receptor subunit alpha-2, is a membrane bound protein that in humans is encoded by the IL13RA2 gene. It is able to regulate the effects of both IL13 and IL14, despite the fact it is unable to bind directly to the latter. Also, this protein plays an important role in the Th2-polarized immune responses characteristic of a variety of pathologies, including parasitic infection and allergic asthma. Recombinant human IL13RA2, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Expression System
Baculovirus
Antigen Species
Human
Tag
HIgG-His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 85% by SDS-PAGE
Molecular Weight
64.3 kDa (559aa)
Additionnal Information
References & Citations
Caput D., et al, (1996) J. Biol. Chem. 271:16921-16926.; ; Donaldson DD., et al, (1998) J. Immunol. 161:2317-2324.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Hormones & Cytokines
NCBI Accession Number
NP_000631.1
Uniprot Accession Number
Q14627
Species
Human
N Terminal Sequence
Ala
AA Sequence
Frequently Asked Questions
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