Recombinant human PSG5 protein

PSG5, also known as pregnancy-specific beta-1-glycoprotein 5, a member of the PSG family that is mainly produced by the placental syncytiotrophoblasts during pregnancy. The function of PSG5 stimulates secretion of TH2-type cytokines from monocytes, and they may also modulate the maternal immune system during pregnancy, thereby protecting the semi-allotypic fetus from rejection. Recombinant human PSG5 protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Pregnancy-specific beta-1-glycoprotein 5, PSG5, FL-NCA-3, PSG

Expression System

Baculovirus

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Molecular Weight

35.1 kDa (310aa)

Additionnal Information

PSG5, Pregnancy-specific beta-1-glycoprotein 5, PSG5, FL-NCA-3, PSG, ATGP3638-10 µg, ATGP3638-20 µg, ATGP3638-50 µg, ATGP3638-100 µg, ATGP3638-250 µg, ATGP3638-500 µg, ATGP3638-1 mg, ATGP3638-10, ATGP3638-20, ATGP3638-50, ATGP3638-100, ATGP3638-250, ATGP3638-500, ATGP3638-1

References & Citations

Blanchon L., et al, (2006) Biochem. Biophys. Res. Commun. 343:745-753.; ; Chan W Y., et al. (1991) Mol Cell Biochem.106:161-170.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 6.8) containing 1mM DTT, 40% glycerol

Scientific Category

Immunology

NCBI Accession Number

NP_001123486

Uniprot Accession Number

Q15238

Species

Human

N Terminal Sequence

Ala

AA Sequence

ADLQVTIEAL PPKVSEGKDV LLLVHNLPQN LAGYIWYKGQ LMDLYHYITS YVVDGQINIY GPAYTGRETV YSNASLLIQN VTREDAGSYT LHIIKRGDRT RGVTGYFTFN LYLKLPKPYI TINNSKPREN KDVLAFTCEP KSENYTYIWW LNGQSLPVSP RVKRPIENRI LILPSVTRNE TGPYECEIRD RDGGMRSDPV TLNVLYGPDL PSIYPSFTYY RSGENLYLSC FAESNPPAEY FWTINGKFQQ SGQKLSIPQI TTKHRGLYTC SVRNSATGKE SSKSMTVEVS APSGIGRLPL LNPIHHHHHH