Recombinant human VAMP-2 protein

VAMP2, also known as vehicle-associated membrane protein 2 isoform 1, which is an integral membrane protein localized to the cytoplasmic surface of synaptic vesicle, consists of a proline-rich N-terminal region, a highly conserved hydrophilic domain, followed by a transmembrane anchor and a C-terminal. VAMP2 is predominantly expressed in Langerhans islets and glomerular cells. The N-terminal domain of the protein forms a specific SNARE complex with the target membrane-associated t- or Q-SNAREs syntaxin 1 and SNAP-25. Recombinant human VAMP2 protein, fused to His-tag at N-terminus, was expressed in E, coli and using conventional chromatography.

Product Specifications

Product Name Alternative

Vesicle-associated membrane protein 2 isoform 1, VAMP-2, SYB2

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

12.8 kDa (118aa) confirmed by MALDI-TOF

Additionnal Information

VAMP2, Vesicle-associated membrane protein 2 isoform 1, VAMP-2, SYB2, ATGP3636-10 µg, ATGP3636-20 µg, ATGP3636-50 µg, ATGP3636-100 µg, ATGP3636-250 µg, ATGP3636-500 µg, ATGP3636-1 mg, ATGP3636-10, ATGP3636-20, ATGP3636-50, ATGP3636-100, ATGP3636-250, ATGP3636-500, ATGP3636-1

References & Citations

Lin RC., et al. (1997) Neuron. 19 (5) :1087-94.; ; Hanson PI., et al. (1997) Cell. 90 (3) :523-35.; ; Scales SJ., et al. (2002) J Biol Chem. 277 (31) :28271-9.; ; Windoffer R., et al. (1999) Cell Tissue Res. 296 (3) :499-510.