Recombinant human PSG1 protein
PSG1, also known as Pregnancy-specific beta-1-glycoprotein 1, is a secreted glycoprotein of the human PSG family within the CEA (carcinoembryonic antigen) superfamily. PSGs (Pregnancy-specific glycoproteins) are a complex consisting of carbohydrate and protein. It is the most abundant protein found in the maternal bloodstream during the later stages of pregnancy and is of vital importance in fetal development. The PSG functions primarily as an immune-modulator to protect the growing fetus. Recombinant human PSG1 protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Expression System
Baculovirus
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 90% by SDS-PAGE
Molecular Weight
44.6 kDa (394aa)
Additionnal Information
References & Citations
Ha CT., et al, (2010) Biol Reprod. 83:27-35.; ; Lisboa FA., et al, (2011) J Biol Chem. 286:7577-7586.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 20% glycerol
Scientific Category
Immunology
NCBI Accession Number
NP_008836.2
Uniprot Accession Number
P11464
Species
Human
N Terminal Sequence
Ala
AA Sequence
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