Recombinant human PSG1 protein

PSG1, also known as Pregnancy-specific beta-1-glycoprotein 1, is a secreted glycoprotein of the human PSG family within the CEA (carcinoembryonic antigen) superfamily. PSGs (Pregnancy-specific glycoproteins) are a complex consisting of carbohydrate and protein. It is the most abundant protein found in the maternal bloodstream during the later stages of pregnancy and is of vital importance in fetal development. The PSG functions primarily as an immune-modulator to protect the growing fetus. Recombinant human PSG1 protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Pregnancy-specific beta-1-glycoprotein 1, PSG1, B1G1, CD66f, DHFRP2, FL-NCA-1/2, PBG1, PS-beta-C/D, PS-beta-G-1, PSBG-1, PSBG1, PSG95, PSGGA, PSGIIA, SP1

Expression System

Baculovirus

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Molecular Weight

44.6 kDa (394aa)

Additionnal Information

PSG1, Pregnancy-specific beta-1-glycoprotein 1, PSG1, B1G1, CD66f, DHFRP2, FL-NCA-1/2, PBG1, PS-beta-C/D, PS-beta-G-1, PSBG-1, PSBG1, PSG95, PSGGA, PSGIIA, SP1, ATGP3630-10 µg, ATGP3630-20 µg, ATGP3630-50 µg, ATGP3630-100 µg, ATGP3630-250 µg, ATGP3630-500 µg, ATGP3630-1 mg, ATGP3630-10, ATGP3630-20, ATGP3630-50, ATGP3630-100, ATGP3630-250, ATGP3630-500, ATGP3630-1

References & Citations

Ha CT., et al, (2010) Biol Reprod. 83:27-35.; ; Lisboa FA., et al, (2011) J Biol Chem. 286:7577-7586.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 20% glycerol

Scientific Category

Immunology

NCBI Accession Number

NP_008836.2

Uniprot Accession Number

P11464

Species

Human

N Terminal Sequence

Ala

AA Sequence

QVTIEAE PTKVSEGKDV LLLVHNLPQN LTGYIWYKGQ MRDLYHYITS YVVDGEIIIY GPAYSGRETA YSNASLLIQN VTREDAGSYT LHIIKGDDGT RGVTGRFTFT LHLETPKPSI SSSNLNPRET MEAVSLTCDP ETPDASYLWW MNGQSLPMTH SLKLSETNRT LFLLGVTKYT AGPYECEIRN PVSASRSDPV TLNLLPKLPK PYITINNLNP RENKDVLNFT CEPKSENYTY IWWLNGQSLP VSPRVKRPIE NRILILPSVT RNETGPYQCE IRDRYGGIRS DPVTLNVLYG PDLPRIYPSF TYYRSGEVLY LSCSADSNPP AQYSWTINEK FQLPGQKLFI RHITTKHSGL YVCSVRNSAT GKESSKSMTV EVSGKWIP