Recombinant human CD316/IGSF8 protein

IGSF8, also known as Immunoglobulin superfamily member 8, is a member of the immunoglobulin protein superfamily. It interact with the tetraspanins CD81 and CD9 and may regulate their role in certain cellular functions including cell migration and viral infection. Also, this protein may function as a tumor suppressor by inhibiting the proliferation of certain cancers. Recombinant human IGSF8 protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Immunoglobulin superfamily member 8, IGSF8, CD316, CD81P3, EWI-2, EWI2, KCT-4, LIR-D1, PGRL, CD81 partner 3, Glu-Trp-Ile EWI motif-containing protein 2, Keratinocytes-associated transmembrane protein 4, Prostaglandin regulatory-like protein

Expression System

Baculovirus

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 95% by SDS-PAGE

Molecular Weight

59.6 kDa (561aa)

Additionnal Information

IGSF8, Immunoglobulin superfamily member 8, IGSF8, CD316, CD81P3, EWI-2, EWI2, KCT-4, LIR-D1, PGRL, ATGP3629-10 µg, ATGP3629-20 µg, ATGP3629-50 µg, ATGP3629-100 µg, ATGP3629-250 µg, ATGP3629-500 µg, ATGP3629-1 mg, ATGP3629-10, ATGP3629-20, ATGP3629-50, ATGP3629-100, ATGP3629-250, ATGP3629-500, ATGP3629-1

References & Citations

Kolesnikova TV., et al, (2004) Blood. 103:3013-3019.; ; Wang HX., et al, (2015) Cell Res. 25:370-385.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 30% glycerol

Scientific Category

Virus

NCBI Accession Number

NP_443100

Uniprot Accession Number

Q969P0

Species

Human

N Terminal Sequence

Ala

AA Sequence

ADLREVLVPE GPLYRVAGTA VSISCNVTGY EGPAQQNFEW FLYRPEAPDT ALGIVSTKDT QFSYAVFKSR VVAGEVQVQR LQGDAVVLKI ARLQAQDAGI YECHTPSTDT RYLGSYSGKV ELRVLPDVLQ VSAAPPGPRG RQAPTSPPRM TVHEGQELAL GCLARTSTQK HTHLAVSFGR SVPEAPVGRS TLQEVVGIRS DLAVEAGAPY AERLAAGELR LGKEGTDRYR MVVGGAQAGD AGTYHCTAAE WIQDPDGSWA QIAEKRAVLA HVDVQTLSSQ LAVTVGPGER RIGPGEPLEL LCNVSGALPP AGRHAAYSVG WEMAPAGAPG PGRLVAQLDT EGVGSLGPGY EGRHIAMEKV ASRTYRLRLE AARPGDAGTY RCLAKAYVRG SGTRLREAAS ARSRPLPVHV REEGVVLEAV AWLAGGTVYR GETASLLCNI SVRGGPPGLR LAASWWVERP EDGELSSVPA QLVGGVGQDG VAELGVRPGG GPVSVELVGP RSHRLRLHSL GPEDEGVYHC APSAWVQHAD YSWYQAGSAR SGPVTVYPYM HALDTHHHHH H