Recombinant human Siglec-6/CD327 protein

SIGLEC6, also known as sialic acid-binding Ig-like lectin 6 isoform 1, is one of immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. It mediates sialic-acid dependent binding to cells and binds to alpha-2, 6-linked sialic acid. This protein localizes in various compartments such as membrane fraction, extracellular region and so on. Recombinant human SIGLEC6 protein, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Sialic acid-binding Ig-like lectin 6 isoform 1, SIGLEC6, CD327, CD33L, CD33L1, CD33L2, CDW327, OBBP1

Expression System

Baculovirus

Antigen Species

Human

Tag

HIgG-His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Molecular Weight

62.6 kDa (563aa)

Additionnal Information

Siglec6, CD327, Sialic acid-binding Ig-like lectin 6 isoform 1, SIGLEC6, CD327, CD33L, CD33L1, CD33L2, CDW327, OBBP1, ATGP3628-10 µg, ATGP3628-20 µg, ATGP3628-50 µg, ATGP3628-100 µg, ATGP3628-250 µg, ATGP3628-500 µg, ATGP3628-1 mg, ATGP3628-10, ATGP3628-20, ATGP3628-50, ATGP3628-100, ATGP3628-250, ATGP3628-500, ATGP3628-1

References & Citations

Lam KK., et al, (2011) J Biol Chem. 286:37118-37127.; ; Rumer KK., et al, (2013) Reprod Sci. 20:646-53.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Scientific Category

Immunology

NCBI Accession Number

NP_001236

Uniprot Accession Number

O43699

Species

Human

N Terminal Sequence

Ala

AA Sequence

QERRFQL EGPESLTVQE GLCVLVPCRL PTTLPASYYG YGYWFLEGAD VPVATNDPDE EVQEETRGRF HLLWDPRRKN CSLSIRDARR RDNAAYFFRL KSKWMKYGYT SSKLSVRVMA LTHRPNISIP GTLESGHPSN LTCSVPWVCE QGTPPIFSWM SAAPTSLGPR TTQSSVLTIT PRPQDHSTNL TCQVTFPGAG VTMERTIQLN VSYAPQKVAI SIFQGNSAAF KILQNTSSLP VLEGQALRLL CDADGNPPAH LSWFQGFPAL NATPISNTGV LELPQVGSAE EGDFTCRAQH PLGSLQISLS LFVHWKPEGR AGGV