Recombinant human Siglec-6/CD327 protein
SIGLEC6, also known as sialic acid-binding Ig-like lectin 6 isoform 1, is one of immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. It mediates sialic-acid dependent binding to cells and binds to alpha-2, 6-linked sialic acid. This protein localizes in various compartments such as membrane fraction, extracellular region and so on. Recombinant human SIGLEC6 protein, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Sialic acid-binding Ig-like lectin 6 isoform 1, SIGLEC6, CD327, CD33L, CD33L1, CD33L2, CDW327, OBBP1
Expression System
Baculovirus
Antigen Species
Human
Tag
HIgG-His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 90% by SDS-PAGE
Molecular Weight
62.6 kDa (563aa)
Additionnal Information
References & Citations
Lam KK., et al, (2011) J Biol Chem. 286:37118-37127.; ; Rumer KK., et al, (2013) Reprod Sci. 20:646-53.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Immunology
NCBI Accession Number
NP_001236
Uniprot Accession Number
O43699
Species
Human
N Terminal Sequence
Ala
AA Sequence
Frequently Asked Questions
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