Recombinant human Siglec-9 protein
SIGLEC9, also known as sialic acid-binding Ig-like lectin 9 isoform 1, is a novel member of the sialic acid-binding Ig-like lectin (Siglec) family, which belongs to the immunoglobulin superfamily (IgSF) expressed broadly on human blood leukocytes. It has a high-level expression in bone marrow, placenta, spleen, and fetal liver. It is a member of the recently characterized CD33-related Siglec family of sialic acid binding protein and is expressed on human monocytes and NK cells. Recombinant human SIGLEC9, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Sialic acid-binding Ig-like lectin 9 isoform 1, SIGLEC9, CD329, CDw329, FOAP-9, OBBP-LIKE
Expression System
Baculovirus
Antigen Species
Human
Tag
HIgG-His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 95% by SDS-PAGE
Molecular Weight
63.3 kDa (573aa)
Additionnal Information
References & Citations
Avril T., et al. (2004) J Immunol. 173:6841-6849.; ; Zhang JQ., et al. (2000) J Biol Chem. 275:22121-22126.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Cardiovascular
NCBI Accession Number
NP_001185487
Uniprot Accession Number
Q9Y336
Species
Human
N Terminal Sequence
Ala
AA Sequence
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