Recombinant human Siglec-9 protein

SIGLEC9, also known as sialic acid-binding Ig-like lectin 9 isoform 1, is a novel member of the sialic acid-binding Ig-like lectin (Siglec) family, which belongs to the immunoglobulin superfamily (IgSF) expressed broadly on human blood leukocytes. It has a high-level expression in bone marrow, placenta, spleen, and fetal liver. It is a member of the recently characterized CD33-related Siglec family of sialic acid binding protein and is expressed on human monocytes and NK cells. Recombinant human SIGLEC9, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Sialic acid-binding Ig-like lectin 9 isoform 1, SIGLEC9, CD329, CDw329, FOAP-9, OBBP-LIKE

Expression System

Baculovirus

Antigen Species

Human

Tag

HIgG-His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 95% by SDS-PAGE

Molecular Weight

63.3 kDa (573aa)

Additionnal Information

Siglec9, ATGP3622-10 µg, ATGP3622-20 µg, ATGP3622-50 µg, ATGP3622-100 µg, ATGP3622-250 µg, ATGP3622-500 µg, ATGP3622-1 mg, ATGP3622-10, ATGP3622-20, ATGP3622-50, ATGP3622-100, ATGP3622-250, ATGP3622-500, ATGP3622-1

References & Citations

Avril T., et al. (2004) J Immunol. 173:6841-6849.; ; Zhang JQ., et al. (2000) J Biol Chem. 275:22121-22126.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Scientific Category

Cardiovascular

NCBI Accession Number

NP_001185487

Uniprot Accession Number

Q9Y336

Species

Human

N Terminal Sequence

Ala

AA Sequence

QTSKLLT MQSSVTVQEG LCVHVPCSFS YPSHGWIYPG PVVHGYWFRE GANTDQDAPV ATNNPARAVW EETRDRFHLL GDPHTKNCTL SIRDARRSDA GRYFFRMEKG SIKWNYKHHR LSVNVTALTH RPNILIPGTL ESGCPQNLTC SVPWACEQGT PPMISWIGTS VSPLDPSTTR SSVLTLIPQP QDHGTSLTCQ VTFPGASVTT NKTVHLNVSY PPQNLTMTVF QGDGTVSTVL GNGSSLSLPE GQSLRLVCAV DAVDSNPPAR LSLSWRGLTL CPSQPSNPGV LELPWVHLRD AAEFTCRAQN PLGSQQVYLN VSLQSKATSG VTQG