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Recombinant human FGF R2 alpha protein

FGFR2, also known as fibroblast growth factor receptor 2 isoform 2, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. It plays an important regulatory role in skeletal development and bone formation. Its dysregulation results in a spectrum of bone and skin pathologies and several types of cancer. Recombinant human FGFR2, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Fibroblast growth factor receptor 2 isoform 2, FGFR2, BBDS, BEK, BFR-1, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25

Expression System

Baculovirus

Antigen Species

Human

Tag

HIgG-His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 95% by SDS-PAGE

Molecular Weight

66.6 kDa (596aa)

Additionnal Information

FGF R2 a, Fibroblast growth factor receptor 2 isoform 2, FGFR2, BBDS, BEK, BFR-1, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25, ATGP3621-10 µg, ATGP3621-20 µg, ATGP3621-50 µg, ATGP3621-100 µg, ATGP3621-250 µg, ATGP3621-500 µg, ATGP3621-1 mg, ATGP3621-10, ATGP3621-20, ATGP3621-50, ATGP3621-100, ATGP3621-250, ATGP3621-500, ATGP3621-1

References & Citations

Kaabeche K., et al. (2004) J Biol Chem. 279:36259-36267.; ; Katoh M., et al. (2009) J Invest Dermatol. 129:1861-1867.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Scientific Category

Cardiovascular

NCBI Accession Number

NP_075259

Uniprot Accession Number

P21802

Species

Human

N Terminal Sequence

Arg22

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