Recombinant human FGF R2 alpha protein
FGFR2, also known as fibroblast growth factor receptor 2 isoform 2, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. It plays an important regulatory role in skeletal development and bone formation. Its dysregulation results in a spectrum of bone and skin pathologies and several types of cancer. Recombinant human FGFR2, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Fibroblast growth factor receptor 2 isoform 2, FGFR2, BBDS, BEK, BFR-1, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25
Expression System
Baculovirus
Antigen Species
Human
Tag
HIgG-His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 95% by SDS-PAGE
Molecular Weight
66.6 kDa (596aa)
Additionnal Information
References & Citations
Kaabeche K., et al. (2004) J Biol Chem. 279:36259-36267.; ; Katoh M., et al. (2009) J Invest Dermatol. 129:1861-1867.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Cardiovascular
NCBI Accession Number
NP_075259
Uniprot Accession Number
P21802
Species
Human
N Terminal Sequence
Arg22
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