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Recombinant human CD66d/CEACAM3 protein

CEACAM3, also known as carcinoembryonic antigen-related cell adhesion molecule 3 isoform 1, is a granulocyte-specific receptor involved in the opsonin-independent recognition of several bacterial pathogens. Members of CEACAM family are widely expressed especially on human neutrophils, and, depending on the tissue, capable of regulating diverse functions including tumor promotion, tumor suppression. Also, it mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Recombinant human CEACAM3, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Carcinoembryonic antigen-related cell adhesion molecule 3 isoform 1, CEACAM3, CD66D, CEA, CGM1, W264, W282, CEA cell adhesion molecule 3

Expression System

Baculovirus

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 95% by SDS-PAGE

Molecular Weight

14.2 kDa (130aa)

Additionnal Information

CEACAM3, CD66d, Carcinoembryonic antigen-related cell adhesion molecule 3 isoform 1, CEACAM3, CD66D, CEA, CGM1, W264, W282, ATGP3613-10 µg, ATGP3613-20 µg, ATGP3613-50 µg, ATGP3613-100 µg, ATGP3613-250 µg, ATGP3613-500 µg, ATGP3613-1 mg, ATGP3613-10, ATGP3613-20, ATGP3613-50, ATGP3613-100, ATGP3613-250, ATGP3613-500, ATGP3613-1

References & Citations

Buntru A., et al, (2012) Arch. Biochem. Biophys. 524:77-83.; ; Kopp K., et al, (2012) J. Biol. Chem. 287:39158-39170.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Scientific Category

Immunology

NCBI Accession Number

NP_001806

Uniprot Accession Number

P40198

Species

Human

N Terminal Sequence

Ala

AA Sequence

ADPKLTIESM PLSVAEGKEV LLLVHNLPQH LFGYSWYKGE RVDGNSLIVG YVIGTQQATP GAAYSGRETI YTNASLLIQN VTQNDIGFYT LQVIKSDLVN EEATGQFHVY QENAPGLPVG AVAGHHHHHH

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