Recombinant human CD66d/CEACAM3 protein
CEACAM3, also known as carcinoembryonic antigen-related cell adhesion molecule 3 isoform 1, is a granulocyte-specific receptor involved in the opsonin-independent recognition of several bacterial pathogens. Members of CEACAM family are widely expressed especially on human neutrophils, and, depending on the tissue, capable of regulating diverse functions including tumor promotion, tumor suppression. Also, it mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Recombinant human CEACAM3, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Carcinoembryonic antigen-related cell adhesion molecule 3 isoform 1, CEACAM3, CD66D, CEA, CGM1, W264, W282, CEA cell adhesion molecule 3
Expression System
Baculovirus
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 95% by SDS-PAGE
Molecular Weight
14.2 kDa (130aa)
Additionnal Information
References & Citations
Buntru A., et al, (2012) Arch. Biochem. Biophys. 524:77-83.; ; Kopp K., et al, (2012) J. Biol. Chem. 287:39158-39170.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Immunology
NCBI Accession Number
NP_001806
Uniprot Accession Number
P40198
Species
Human
N Terminal Sequence
Ala
AA Sequence
ADPKLTIESM PLSVAEGKEV LLLVHNLPQH LFGYSWYKGE RVDGNSLIVG YVIGTQQATP GAAYSGRETI YTNASLLIQN VTQNDIGFYT LQVIKSDLVN EEATGQFHVY QENAPGLPVG AVAGHHHHHH
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