Recombinant human NKG2A/KLRC1 protein
KLRC1, also known as NKG2-A/NKG2-B type II integral membrane protein isoform NKG2-A, is a member of the killer cell lectin-like receptor family. It associates with CD94 and is expressed on NK cells and some activated T cell populations. This protein functions as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Recombinant human KLRC1 protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Expression System
Baculovirus
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 90% by SDS-PAGE
Molecular Weight
17.1 kDa (149aa)
Additionnal Information
References & Citations
Harrison RJ., et al, (2010) Clin Exp Immunol. 161:306-314.; ; Rapaport AS., et al, (2015) Immunity. 43:1112-1124
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Immunology
NCBI Accession Number
NP_998823
Uniprot Accession Number
P26715
Species
Human
N Terminal Sequence
Ala
AA Sequence
Frequently Asked Questions
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