Recombinant human NKG2A/KLRC1 protein

KLRC1, also known as NKG2-A/NKG2-B type II integral membrane protein isoform NKG2-A, is a member of the killer cell lectin-like receptor family. It associates with CD94 and is expressed on NK cells and some activated T cell populations. This protein functions as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Recombinant human KLRC1 protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

NKG2-B, NKG2-A/NKG2-B type II integral membrane protein isoform NKG2-A, NKG2-A/B-activating NK receptor, NKG2-A, NK cell receptor A, Killer cell lectin-like receptor subfamily C member 1, Killer cell lectin like receptor C1, CD159a, CD159 antigen-like family member A

Expression System

Baculovirus

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Molecular Weight

17.1 kDa (149aa)

Additionnal Information

KLRC1, NKG2-A/NKG2-B type II integral membrane protein isoform NKG2-A, KLRC1, CD159A, NKG2, NKG2A, ATGP3608-10 µg, ATGP3608-20 µg, ATGP3608-50 µg, ATGP3608-100 µg, ATGP3608-250 µg, ATGP3608-500 µg, ATGP3608-1 mg, ATGP3608-10, ATGP3608-20, ATGP3608-50, ATGP3608-100, ATGP3608-250, ATGP3608-500, ATGP3608-1

References & Citations

Harrison RJ., et al, (2010) Clin Exp Immunol. 161:306-314.; ; Rapaport AS., et al, (2015) Immunity. 43:1112-1124

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Scientific Category

Immunology

NCBI Accession Number

NP_998823

Uniprot Accession Number

P26715

Species

Human

N Terminal Sequence

Ala

AA Sequence

PSTLIQR HNNSSLNTRT QKARHCGHCP EEWITYSNSC YYIGKERRTW EESLLACTSK NSSLLSIDNE EEMKFLSIIS PSSWIGVFRN SSHHPWVTMN GLAFKHEIKD SDNAELNCAV LQVNRLKSAQ CGSSIIYHCK HKL