Recombinant human EPCR protein
PROCR, also known as endothelial protein C receptor, is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. It is a transmembrane glycoprotein expressed on vascular endothelial cells and functions as a negative regulator of thrombosis. Recombinant human PROCR protein, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Endothelial protein C receptor, PROCR, CCCA, CCD41, EPCR
Expression System
Baculovirus
Antigen Species
Human
Tag
HIgG-His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 95% by SDS-PAGE
Molecular Weight
49.3 kDa (435aa)
Additionnal Information
References & Citations
Ghosh S., et al, (2007) J Biol Chem. 282:11849-11857.; ; Keshava S., et al, (2013) J Thromb Haemost. 11 (11) :2062-2065.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Cardiovascular
NCBI Accession Number
NP_006395
Uniprot Accession Number
Q9UNN8
Species
Human
N Terminal Sequence
Ala
AA Sequence
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