Recombinant mouse TLR2 protein
Tlr2, also known as toll-like receptor 2, is a member of the Toll-like receptor (TLR) family. It is typically thought to recognize bacterial components, it has been described to alter the induction of both innate and adaptive immunity to a number of viruses, including vaccinia virus (VACV) . It may recognize virus preparations in vitro and have a minor role in preventing dissemination of VACV following systemic infection with large doses of virus. it is wholly disposable in both control of virus replication and induction of adaptive immunity following intradermal infection. Recombinant mouse Tlr2, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Toll-like receptor 2, Tlr2, Ly105
Expression System
Baculovirus
Antigen Species
Mouse
Tag
HIgG-His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 85% by SDS-PAGE
Molecular Weight
90.7 kDa (805aa)
Additionnal Information
References & Citations
Davies ML., et al. (2014) J Virol. 88:3557-3567.; ; Yueh MF., et al. (2014) J Biol Chem. 289:4699-4709.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Immunology
NCBI Accession Number
NP_036035
Uniprot Accession Number
Q9QUN7
Species
Mouse
N Terminal Sequence
Ala
AA Sequence
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