Recombinant human CD320/TCblR/8D6A protein

CD320, also known as CD320 antigen isoform 1, belongs to the low-density lipoprotein receptor family, with 2 low-density lipoprotein receptor type A domains separated by a complement-like cysteine-rich region. It binds TC- cobalamin (Cbl) and internalizes the complex by endocytosis. It is known to enhance proliferation of germinal center (GC) B cells and follicular dendritic cells. It augments the proliferation of PC precursors generated by IL-10. It collaborates with CD44 in supporting lymphomagenesis by a Burkitt lymphoma cell line, L3055. Recombinant human CD320, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

CD320 antigen isoform 1, CD320, 8D6, 8D6A, TCBLR

Expression System

Baculovirus

Antigen Species

Human

Tag

HIgG-His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Molecular Weight

47.4 kDa (438aa)

Additionnal Information

CD320, TCblRD6A, CD320 antigen isoform 1, CD320, 8D6, 8D6A, TCBLR, ATGP3595-10 µg, ATGP3595-20 µg, ATGP3595-50 µg, ATGP3595-100 µg, ATGP3595-250 µg, ATGP3595-500 µg, ATGP3595-1 mg, ATGP3595-10, ATGP3595-20, ATGP3595-50, ATGP3595-100, ATGP3595-250, ATGP3595-500, ATGP3595-1