Recombinant human CD1a protein
CD1A, also known as T-cell surface glycoprotein CD1a isoform 1, is the CD1 family of transmembrane glycoproteins. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. Also, it is structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. Recombinant human CD1A, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
T-cell surface glycoprotein CD1a isoform 1, CD1A, CD1, FCB6, HTA1, R4, T6
Expression System
Baculovirus
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 85% by SDS-PAGE
Molecular Weight
33.2 kDa (291aa)
Additionnal Information
References & Citations
West JA., et al, (2014) PLoS ONE 9:E109586.; ; Seshadri C., et al, (2014) Genes Immun. 15:195-198.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Immunology
NCBI Accession Number
NP_001754
Uniprot Accession Number
P06126
Species
Human
N Terminal Sequence
Ala
AA Sequence
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