Recombinant human Glycophorin A/GYPA protein

GYPA, also known as glycophorin-A isoform 1, is the major transmembrane sialoglycoprotein of red blood cells. It has been shown to contribute to the expression of the MN and Wright blood group antigens, to act as a receptor for the malaria parasite Plasmodium falciparum and Sendai virus, and along with the anion transporter, band 3, may contribute to the mechanical properties of the red blood cell membrane. It expression is locally increased in carotid atherosclerotic lesions of symptomatic compared to asymptomatic patients. Recombinant human GYPA, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Glycophorin-A isoform 1, GYPA, CD235a, GPA, GPErik, GPSAT, HGpMiV, HGpMiXI, HGpSta (C), MN, MNS, PAS-2, MN sialoglycoprotein, PAS-2, Sialoglycoprotein alpha

Expression System

Baculovirus

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 85% by SDS-PAGE

Molecular Weight

9.1 kDa (81aa)

Additionnal Information

Glycophorin A, Glycophorin-A isoform 1, GYPA, CD235a, GPA, GPErik, GPSAT, HGpMiV, HGpMiXI, HGpSta (C), MN, MNS, PAS-2, ATGP3592-10 µg, ATGP3592-20 µg, ATGP3592-50 µg, ATGP3592-100 µg, ATGP3592-250 µg, ATGP3592-500 µg, ATGP3592-1 mg, ATGP3592-10, ATGP3592-20, ATGP3592-50, ATGP3592-100, ATGP3592-250, ATGP3592-500, ATGP3592-1