Recombinant human TINAGL1 protein

TINAGL1, also known as tubulointerstitial nephritis antigen-like isoform 1, is a glycoprotein member of the peptidase C1 family of molecules. During pregnancy it binds to Laminin-1 and Integrins alpha 5 and beta 1 and plays a role in supporting fertility. In the vasculature, TINAGL1 localizes to basal laminae along adrenocortical sinusoidal capillaries where it binds to fibronectin and collagen and supports adrenocortical cell adhesion. Recombinant human TINAGL1 protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Tubulointerstitial nephritis antigen-like isoform 1, TINAGL1, ARG1, LCN7, LIECG3, TINAGRP

Expression System

Baculovirus

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Molecular Weight

51.2 kDa (455aa)

Additionnal Information

TINAGL1, Tubulointerstitial nephritis antigen-like isoform 1, TINAGL1, ARG1, LCN7, LIECG3, TINAGRP, ATGP3583-10 µg, ATGP3583-20 µg, ATGP3583-50 µg, ATGP3583-100 µg, ATGP3583-250 µg, ATGP3583-500 µg, ATGP3583-1 mg, ATGP3583-10, ATGP3583-20, ATGP3583-50, ATGP3583-100, ATGP3583-250, ATGP3583-500, ATGP3583-1

References & Citations

Wex T. et al., (2001) Biochemistry. 40: 1350-1357.; ; Takahashi A. et al., (2016) J Reprod Dev. 62: 43-49.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 30% glycerol, 1mM DTT

Scientific Category

Signal Transduction

NCBI Accession Number

NP_071447

Uniprot Accession Number

Q9GZM7

Species

Human

N Terminal Sequence

Ala

AA Sequence

ADLAQQGRGR RELAPGLHLR GIRDAGGRYC QEQDLCCRGR ADDCALPYLG AICYCDLFCN RTVSDCCPDF WDFCLGVPPP FPPIQGCMHG GRIYPVLGTY WDNCNRCTCQ ENRQWQCDQE PCLVDPDMIK AINQGNYGWQ AGNHSAFWGM TLDEGIRYRL GTIRPSSSVM NMHEIYTVLN PGEVLPTAFE ASEKWPNLIH EPLDQGNCAG SWAFSTAAVA SDRVSIHSLG HMTPVLSPQN LLSCDTHQQQ GCRGGRLDGA WWFLRRRGVV SDHCYPFSGR ERDEAGPAPP CMMHSRAMGR GKRQATAHCP NSYVNNNDIY QVTPVYRLGS NDKEIMKELM ENGPVQALME VHEDFFLYKG GIYSHTPVSL GRPERYRRHG THSVKITGWG EETLPDGRTL KYWTAANSWG PAWGERGHFR IVRGVNECDI ESFVLGVWGR VGMEDMGHHH HHHHH