Recombinant human TINAGL1 protein
TINAGL1, also known as tubulointerstitial nephritis antigen-like isoform 1, is a glycoprotein member of the peptidase C1 family of molecules. During pregnancy it binds to Laminin-1 and Integrins alpha 5 and beta 1 and plays a role in supporting fertility. In the vasculature, TINAGL1 localizes to basal laminae along adrenocortical sinusoidal capillaries where it binds to fibronectin and collagen and supports adrenocortical cell adhesion. Recombinant human TINAGL1 protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Tubulointerstitial nephritis antigen-like isoform 1, TINAGL1, ARG1, LCN7, LIECG3, TINAGRP
Expression System
Baculovirus
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 90% by SDS-PAGE
Molecular Weight
51.2 kDa (455aa)
Additionnal Information
References & Citations
Wex T. et al., (2001) Biochemistry. 40: 1350-1357.; ; Takahashi A. et al., (2016) J Reprod Dev. 62: 43-49.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 30% glycerol, 1mM DTT
Scientific Category
Signal Transduction
NCBI Accession Number
NP_071447
Uniprot Accession Number
Q9GZM7
Species
Human
N Terminal Sequence
Ala
AA Sequence
Frequently Asked Questions
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