Recombinant human CD160 protein

CD160, also known as CD160 antigen, is a human natural killer (NK) -cell-activating receptor that is also expressed on T-cell subsets. It is a tumor-specific antigen known to mediate cellular activation signals in CLL, and is a novel target for therapeutic manipulation and monitoring of minimal residual disease. It was identified as a T cell coinhibitory molecule that interacts with the herpesvirus entry mediator (HVEM) on antigen-presenting cells to deliver a potent inhibitory signal to CD4 (+) T cells. Recombinant human CD160, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

CD160 antigen, CD160, BY55, NK1, NK28

Expression System

Baculovirus

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Molecular Weight

15.9 kDa (142aa)

Additionnal Information

CD160, CD160 antigen, CD160, BY55, NK1, NK28, ATGP3576-10 µg, ATGP3576-20 µg, ATGP3576-50 µg, ATGP3576-100 µg, ATGP3576-250 µg, ATGP3576-500 µg, ATGP3576-1 mg, ATGP3576-10, ATGP3576-20, ATGP3576-50, ATGP3576-100, ATGP3576-250, ATGP3576-500, ATGP3576-1