Recombinant canine IL-31 protein

IL31, also known as interleukin 31, is a member of the gp130/interleukin-6 cytokine family that is produced by cell types such as T helper 2 lymphocytes and cutaneous lymphocyte antigen positive skin homing T cells. IL-31 signals via a heterodimeric receptor complex composed of a gp130 related molecule termed IL-31RA (also GPL and GLMR) and an Oncostatin M receptor (OSM R beta) . The IL-31 receptor is constitutively expressed by keratinocytes and upregulated by IFN gamma on monocytes. Recombinant canine IL31, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Interleukin-31, IL-31

Expression System

Baculovirus

Antigen Species

Canine

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 95% by SDS-PAGE

Molecular Weight

16.1 kDa (142aa)

Additionnal Information

IL 31, IL31, IL-31, Interleukin-31, Interleukin 31, Interleukin31, ATGP3570-10 µg, ATGP3570-20 µg, ATGP3570-50 µg, ATGP3570-100 µg, ATGP3570-250 µg, ATGP3570-500 µg, ATGP3570-1 mg, ATGP3570-010, ATGP3570-020, ATGP3570-050, ATGP3570-100, ATGP3570-250, ATGP3570-500, ATGP3570-01M