Recombinant mouse CAMK2N1 protein
Camk2n1, also known as Calcium/calmodulin-dependent protein kinase II inhibitor 1, belongs to the CAMK2N family. This protein interacts with CAMK2B; the presence of Ca2+/calmodulin increases the interaction but is not essential. It also interacts with CAMK2A; this interaction requires CAMK2A activation by Ca2+. Camk2n1 is potent and specific inhibitor of CaM-kinase II (CAMK2) . Recombinant mouse Camk2n1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Calcium/calmodulin-dependent protein kinase II inhibitor 1, Calcium/calmodulin-dependent protein kinase II inhibitor alpha, mCaMKIINalpha
Expression System
E.coli
Antigen Species
Mouse
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
10.9 kDa (101aa) Confirmed by MALDI-TOF
Additionnal Information
References & Citations
Wang C., et al. (2008) J Biol Chem. 283 (17) :11565-74.; ; Meng F., et al. (2003) Brain Res. 967 (1-2) : 161-9.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.5) containing 1mM DTT, 0.1M NaCl, 10% glycerol
Scientific Category
Signal Transduction
NCBI Accession Number
NP_079727
Uniprot Accession Number
Q6QWF9
Species
Mouse
AA Sequence
MSEVLPY GDEKLSPYGD GGDVGQIFSC RLQDTNNFFG AGQSKRPPKL GQIGRSKRVV IEDDRIDDVL KTMTDKAPPG V
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