Recombinant human CD3 gamma/CD3G protein
CD3G, also known as T-cell surface glycoprotein CD3 gamma chain, is associated on the T cell surface with a complex of protein called CD3. The protein is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal transduction pathways. Defects in this gene are associated with T cell immunodeficiency. Recombinant human CD3G protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Expression System
Baculovirus
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 85% by SDS-PAGE
Molecular Weight
11.8 kDa (103aa)
Additionnal Information
References & Citations
Munoz-Ruiz M., et al. (2013) BMC Immunol. 14: 3.; ; Gokturk B., et al. (2014) Scand J Immunol. 80:354-361.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Immunology
NCBI Accession Number
NP_000064
Uniprot Accession Number
P09693
Species
Human
N Terminal Sequence
Ala
AA Sequence
ADPQSIKGNH LVKVYDYQED GSVLLTCDAE AKNITWFKDG KMIGFLTEDK KKWNLGSNAK DPRGMYQCKG SQNKSKPLQV YYRMCQNCIE LNAATISHHH HHH
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items