Recombinant human Glycophorin C/GYPC protein

GYPC, also known as glycophorin-C isoform 1, is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B. Alternate splicing results in multiple transcript variants. Recombinant human GYPC protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Glycophorin-C isoform 1, GYPC, CD236, CD236R, GE, GPC, GPD, GYPD, PAS-2, PAS-2, Glycoconnectin, Glycophorin-D, GPD, Glycoprotein beta, PAS-2', Sialoglycoprotein D, GLPC

Expression System

Baculovirus

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 95% by SDS-PAGE

Molecular Weight

7.2 kDa (66aa)

Additionnal Information

GYPC, Glycophorin-C isoform 1, GYPC, CD236, CD236R, GE, GPC, GPD, GYPD, PAS-2, PAS-2, ATGP3547-10 µg, ATGP3547-20 µg, ATGP3547-50 µg, ATGP3547-100 µg, ATGP3547-250 µg, ATGP3547-500 µg, ATGP3547-1 mg, ATGP3547-10, ATGP3547-20, ATGP3547-50, ATGP3547-100, ATGP3547-250, ATGP3547-500, ATGP3547-1