Recombinant canine IL-2 (C147S) protein

IL2, also known as Interleukin2, is an immunoregulatory lymphokine produced by T-cell in response to antigenic or mitogenic stimulation IL2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. IL2 stimulates growth and differentiation of B-cells, NK cells, lymphokine activated kill cells, monocytres, macrophages and oligodendrocytes. Recombinant canine IL2 protein was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Specifications

Canine IL-2 stimulates cell cytotoxicity in the CTLL-2 mouse cytotoxic T cell. The ED50 range ≤ 0.3 ng/mL.

Product Name Alternative

Interleukin-2, IL-2, T-cell growth factor, TCGF

Expression System

E.coli

Antigen Species

Canine

Tag

His-Tag

Applications

SDS-PAGE, Bioactivity

Concentration

0.5 mg/mL (determined by Bradford assay)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 95% by SDS-PAGE

Bioactivity

Measured in a cell proliferation assay using CTLL-2 mouse cytotoxic T cells. The ED50 range ≤ 0.3 ng/mL.

Molecular Weight

18.1 kDa (160aa) confirmed by MALDI-TOF

Additionnal Information

IL2 (C147S), Interleukin-2, Interleukin2, Interleukin 2, IL-2, IL 2, ATGP3544-10 µg, ATGP3544-20 µg, ATGP3544-50 µg, ATGP3544-100 µg, ATGP3544-250 µg, ATGP3544-500 µg, ATGP3544-1 mg, ATGP3544-010, ATGP3544-020, ATGP3544-050, ATGP3544-100, ATGP3544-250, ATGP3544-500, ATGP3544-01M