Recombinant canine IL-6 protein
IL6, as known as Interleukin-6, is a phosphorylated and variably glycosylated cytokine. It is secreted by T cells and macrophages to stimulate immune response during infection and after trauma, especially burns or other tissue damage leading to inflammation. Also, this protein can function as an anti-inflammatory molecule, as in skeletal muscle where it is secreted in response to exercise. Recombinant canine IL6, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Interleukin-6, IL6, IL-6
Expression System
Baculovirus
Antigen Species
Canine
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 95% by SDS-PAGE
Molecular Weight
22 kDa (195aa)
Additionnal Information
References & Citations
Schuttler J., et al, (2015) Vet. Clin. Pathol. 44:223-228.; ; Pei Z., et al, (2015) J. Vet. Med. Sci. 77:139-145.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Immunology
NCBI Accession Number
NP_001003301
Uniprot Accession Number
P41323
Species
Canine
N Terminal Sequence
Phe21
Frequently Asked Questions
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