Recombinant human CD79B protein
CD79B, as known as B-cell antigen receptor complex-associated protein beta chain isoform 1, is B-cell-specific glycoprotein B29. It is a single-pass type 1 membrane protein containing one Ig-like V-type domain and one ITAM domain. This protein is required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) . CD79A and B proteins are required for BCR-meditated signaling and consequently for the development and activation of B lineage cells. Recombinant human CD79B, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
B-cell antigen receptor complex-associated protein beta chain isoform 1, CD79B, AGM6, B29, IGB
Expression System
Baculovirus
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 90% by SDS-PAGE
Molecular Weight
16.3 kDa (140aa)
Additionnal Information
References & Citations
Jahn L., et al, (2015) Blood 125:949-958.; ; Yamada S., et al, (2015) Leuk. Lymphoma 56:2141-2145.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Immunology
NCBI Accession Number
NP_000617
Uniprot Accession Number
P40259
Species
Human
N Terminal Sequence
Ala
AA Sequence
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