Recombinant human ORM2 protein
ORM2, also known as Alpha-1-acid glycoprotein 2, is a key acute phase plasma protein. It belongs to calycin superfamily, lipocalin family. Lipocalins transport small hydrophobic molecules such as steroids, bilins, retinoids, and lipids. This protein functions as transport protein in the blood stream. It is expressed by the liver and secreted in plasma. It seems that ORM2 function in modulating the activity of the immune system during the acute-phase reaction. Recombinant human ORM2 protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Alpha-1-acid glycoprotein 2, ORM2, AGP-B, AGP-B', AGP2
Expression System
Baculovirus
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 90% by SDS-PAGE
Molecular Weight
22.7 kDa (192aa)
Additionnal Information
References & Citations
Zhang X., et al. (2012) PLoS One. 7:e31868.; ; Gao F., et al. (2014) Ann Clin Lab Sci. 44:388-393.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Cardiovascular
NCBI Accession Number
NP_000599.1
Uniprot Accession Number
P19652
Species
Human
N Terminal Sequence
Ala
AA Sequence
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