Recombinant human CD300C protein

CD300C, also known as CMRF35-like molecule 6, is a type I transmembrane glycoprotein that belongs to the immune regulatory signaling (IRS) family of molecules within the immunoglobulin (Ig) superfamily. It is present on the surface of natural killer cells, granulocytes, most myeloid cells, dendritic cells, and a subpopulation of T and B lymphocytes. This protein regulates a diverse array of cell processes via their triggering and inhibitory receptor functions. Recombinant human CD300c protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

LMIR2, LIR, Immunoglobulin superfamily member 16, IGSF16, CMRF35-like molecule 6, CMRF35A1, CMRF35A, CMRF35, CLM-6, CD300LMIR2, CD300C molecule, CD300C, CD300 antigen-like family member C, ,

Expression System

Baculovirus

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 95% by SDS-PAGE

Molecular Weight

18kDa (163aa)

Additionnal Information

LMIR2, LIR, Immunoglobulin superfamily member 16, IGSF16, CMRF35-like molecule 6, CMRF35-A1, CMRF35A1, CMRF-35A, CMRF35A, CMRF-35, CMRF35, CLM-6, CD300LMIR2, CD300c molecule, CD300C, CD300 antigen-like family member C, ATGP3537-10 µg, ATGP3537-20 µg, ATGP3537-50 µg, ATGP3537-100 µg, ATGP3537-250 µg, ATGP3537-500 µg, ATGP3537-1 mg, ATGP3537-010, ATGP3537-020, ATGP3537-050, ATGP3537-100, ATGP3537-250, ATGP3537-500, ATGP3537-01M

References & Citations

Lankry D., et al. (2010) J Immunol. 185:2877-2886.; ; Simhadri VR., et al. (2013) J Innate Immun. 5:389-400.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Scientific Category

Immunology

NCBI Accession Number

NP_006669

Uniprot Accession Number

Q08708

Species

Human

N Terminal Sequence

Met29

AA Sequence

MTVAGPVGGS LSVQCRYEKE HRTLNKFWCR PPQILRCDKI VETKGSAGKR NGRVSIRDSP ANLSFTVTLE NLTEEDAGTY WCGVDTPWLR DFHDPIVEVE VSVFPAGTTT ASSPQSSMGT SGPPTKLPVH TWPSVTRKDS PEPSPHPGSL FSNVRLEHHH HHH