Recombinant mouse AG-2/AGR2 protein

Agr2, also known as anterior gradient protein 2 homolog, is the orthologue of the secreted Xenopus laevis Anterior Gradient protein (XAG-2) . This is a small, possibly secreted molecule of yet weakly defined functions that is widely expressed in human tissues. Expression of Agr2 shows a positive correlation with expression of estrogen receptor in breast carcinoma and a negative correlation with expression of EGF receptor. Recombinant mouse Agr2, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Anterior gradient protein 2 homolog, Agr2h, Gob-4, HAG-2, mAG-2, XAG-2

Expression System

E.coli

Antigen Species

Mouse

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by absorbance at 280 nm)

Purity

> 90% by SDS-PAGE

Molecular Weight

20.5 kDa (180aa)

Additionnal Information

Agr2, Anterior gradient protein 2 homolog, Agr2h, Gob-4, HAG-2, mAG-2, XAG-2, ATGP3525-10 µg, ATGP3525-20 µg, ATGP3525-50 µg, ATGP3525-100 µg, ATGP3525-250 µg, ATGP3525-500 µg, ATGP3525-1 mg, ATGP3525-10, ATGP3525-20, ATGP3525-50, ATGP3525-100, ATGP3525-250, ATGP3525-500, ATGP3525-1

References & Citations

Fritzsche FR. et al., (2007) Histol Histopathol. 22 (7) :703-8; ; Fletcher GC. et al., (2003) Br J Cancer. 88 (4) : 579-85; ; Liu D. et al., (2005) Cancer Res. 65 (9) :3796-805

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 1mM DTT, 1mM EDTA

Scientific Category

Cancer

NCBI Accession Number

NP_035913

Uniprot Accession Number

O88312

Species

Mouse

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSHMKDTTV KSGAKKDPKD SRPKLPQTLS RGWGDQLIWT QTYEEALYRS KTSNRPLMVI HHLDECPHSQ ALKKVFAEHK EIQKLAEQFV LLNLVYETTD KHLSPDGQYV PRIVFVDPSL TVRADITGRY SNRLYAYEPS DTALLYDNMK KALKLLKTEL