Recombinant human SLAM/CD150 protein

SLAMF1, also known as signaling lymphocytic activation molecule family member 1, is a cell surface sialylated phosphoglycoprotein and belongs to the CD2 subset of the Ig superfamily of type I transmembrane glycoproteins. This protein is constitutively expressed on peripheral blood memory T cells, T-cell clones, immature thymocytes, and a proportion of B cells, and is rapidly induced on naive T cells after activation. High-affinity for self-ligand is important in bidirectional T-cell to B-cell stimulation. Recombinant mouse SLAMF1 protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Signaling lymphocytic activation molecule family member 1, SLAMF1, SLAM, CD150, CDw150

Expression System

Baculovirus

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by BCA assay)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 95% by SDS-PAGE

Molecular Weight

25.3 kDa (226aa)

Additionnal Information

SLAM, CD150, Signaling lymphocytic activation molecule family member 1, SLAMF1, SLAM, CD150, CDw150, ATGP3522-10 µg, ATGP3522-20 µg, ATGP3522-50 µg, ATGP3522-100 µg, ATGP3522-250 µg, ATGP3522-500 µg, ATGP3522-1 mg, ATGP3522-10, ATGP3522-20, ATGP3522-50, ATGP3522-100, ATGP3522-250, ATGP3522-500, ATGP3522-1

References & Citations

Ma C., et al. (2012) J Biol Chem. 287: 18359-18365.; ; Romanets-Korbut O., et al. (2015) PLoS One. 10: e0118302.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Scientific Category

Immunology

NCBI Accession Number

NP_003028

Uniprot Accession Number

Q13291

Species

Human

N Terminal Sequence

Ala

AA Sequence

ASYGTGG RMMNCPKILR QLGSKVLLPL TYERINKSMN KSIHIVVTMA KSLENSVENK IVSLDPSEAG PPRYLGDRYK FYLENLTLGI RESRKEDEGW YLMTLEKNVS VQRFCLQLRL YEQVSTPEIK VLNKTQENGT CTLILGCTVE KGDHVAYSWS EKAGTHPLNP ANSSHLLSLT LGPQHADNIY ICTVSNPISN NSQTFSPWPG CRTDPSETKP