Recombinant human FOLR1 protein
FOLR1, as known as folate receptor alpha, is a member of the folate receptor family. This protein meditates the cellular uptake of folic acid and reduced folates. Dietary folates are required for many key metabolic processes including nucleotide ad methionine synthesis, the interconversion of glycine and serine, and histidine breakdown. Also, mature form is an N-glycosylated protein that is anchored to the cell surface by a GPI linkages. Recombinant human FOLR1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Folate receptor alpha, FOLR1, FBP, FOLR
Expression System
Baculovirus
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 90% by SDS-PAGE
Molecular Weight
25.6 kDa (218aa)
Additionnal Information
References & Citations
Hansen MJ., et al, (2015) Inflamm. Res. 64:697-706.; ; Ab O., et al, (2015) Mol. Cancer Ther. 14:1605-1613.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Cancer
NCBI Accession Number
NP_000793.1
Uniprot Accession Number
P15328
Species
Human
N Terminal Sequence
Ala
AA Sequence
Frequently Asked Questions
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