Recombinant mouse Histone Deacetylase 8/HDAC8 protein

Hdac8, also known as histone deacetylase 8 isoform 1, is a member of the class I Histone Deacetylases. Its specific inhibition reduces gene expression and production of proinflammatory cytokines in vitro and in vivo. It expressed in the renal epithelial cells of the mouse kidney. Its activity contributes to renal protection and functional recovery and is required for renal regeneration after AKI. Recombinant mouse Hdac8, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Histone deacetylase 8 isoform 1, Hdac8, 2610007D20Rik, HD8, Protein deacetylase HDAC8, Protein decrotonylase HDAC8

Expression System

Baculovirus

Antigen Species

Mouse

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Molecular Weight

42.5 kDa (383aa)

Additionnal Information

Hdac8, Histone deacetylase 8 isoform 1, Hdac8, 2610007D20Rik, ATGP3515-10 µg, ATGP3515-20 µg, ATGP3515-50 µg, ATGP3515-100 µg, ATGP3515-250 µg, ATGP3515-500 µg, ATGP3515-1 mg, ATGP3515-10, ATGP3515-20, ATGP3515-50, ATGP3515-100, ATGP3515-250, ATGP3515-500, ATGP3515-1