Recombinant mouse IFN-gamma/IFNG protein
Ifng, also known as interferon gamma, is secreted by lymphocytes stimulated by mitogen and is involved in the differentiation, maturation, and proliferation of hematopoietic cells. This protein is a soluble cytokine with antiviral, immunoregulatory and anti-tumor properties and is a potent activator of macrophages. Mutations in this gene are associated with aplastic anemia. Recombinant mouse Ifng protein was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Interferon gamma, Ifg, IFN-g
Expression System
E.coli
Antigen Species
Mouse
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 90% by SDS-PAGE
Molecular Weight
18.2 kDa (158aa)
Additionnal Information
References & Citations
Barbosa MA., et al. (2011) J Comp pathol. 145 (4) :336-44.; ; Dong H., et al. (2015) Oncogene. 34 (42) :5363-71.
Other References
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM MES buffer (pH 5.0) containing 40% glycerol, 0.2M NaCl, 1mM DTT
Scientific Category
Hormones & Cytokines
NCBI Accession Number
NP_032363.1
Uniprot Accession Number
P01580
Species
Mouse
AA Sequence
HGTVI ESLESLNNYF NSSGIDVEEK SLFLDIWRNW QKDGDMKILQ SQIISFYLRL FEVLKDNQAI SNNISVIESH LITTFFSNSK AKKDAFMSIA KFEVNNPQVQ RQAFNELIRV VHQLLPESSL RKRKRSRC
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