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Recombinant mouse IFN-gamma/IFNG protein

Ifng, also known as interferon gamma, is secreted by lymphocytes stimulated by mitogen and is involved in the differentiation, maturation, and proliferation of hematopoietic cells. This protein is a soluble cytokine with antiviral, immunoregulatory and anti-tumor properties and is a potent activator of macrophages. Mutations in this gene are associated with aplastic anemia. Recombinant mouse Ifng protein was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Interferon gamma, Ifg, IFN-g

Expression System

E.coli

Antigen Species

Mouse

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Molecular Weight

18.2 kDa (158aa)

Additionnal Information

IFN-g, ATGP3513-10 µg, ATGP3513-20 µg, ATGP3513-50 µg, ATGP3513-100 µg, ATGP3513-250 µg, ATGP3513-500 µg, ATGP3513-1 mg, ATGP3513-10, ATGP3513-20, ATGP3513-50, ATGP3513-100, ATGP3513-250, ATGP3513-500, ATGP3513-1

References & Citations

Barbosa MA., et al. (2011) J Comp pathol. 145 (4) :336-44.; ; Dong H., et al. (2015) Oncogene. 34 (42) :5363-71.

Other References

Jeong S, et al. Suppression of Pro-Inflammatory M1 Polarization of LPS-Stimulated RAW 264.7 Macrophage Cells by Fucoxanthin-Rich Sargassum hemiphyllum. (Mar Drugs. 2023) {https://pubmed.ncbi.nlm.nih.gov/37888467/}

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM MES buffer (pH 5.0) containing 40% glycerol, 0.2M NaCl, 1mM DTT

Scientific Category

Hormones & Cytokines

NCBI Accession Number

NP_032363.1

Uniprot Accession Number

P01580

Species

Mouse

AA Sequence

HGTVI ESLESLNNYF NSSGIDVEEK SLFLDIWRNW QKDGDMKILQ SQIISFYLRL FEVLKDNQAI SNNISVIESH LITTFFSNSK AKKDAFMSIA KFEVNNPQVQ RQAFNELIRV VHQLLPESSL RKRKRSRC

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