Recombinant human IL-5 protein

IL5, also known as interleukin-5, is a member of the hematopoietin receptor superfamily and is comprised of a cytokine-specific alpha chain and the common beta chain that is shared among these cytokines for signaling. It related hematopoietic cytokines that are important for allergic inflammation. It is a lineage-specific cytokine for eosinophilpoiesis and plays an important part in diseases associated with increased eosinophils, such as asthma. Recombinant human IL5, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Specifications

Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED50 range ≤1.5 ng/mL.

Product Name Alternative

Interleukin-5, IL-5, EDF, TRF, T-cell replacing factor, B cell differentiation factor I, Eosinophil differentiation factor, Colony-stimulating factor eosinophil, BCGF-I

Expression System

Baculovirus

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Bioactivity

Concentration

0.5 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Bioactivity

Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED50 range ≤1.5 ng/mL.

Molecular Weight

14.2 kDa (124aa)

Additionnal Information

IL5, ATGP3510-10 µg, ATGP3510-20 µg, ATGP3510-50 µg, ATGP3510-100 µg, ATGP3510-250 µg, ATGP3510-500 µg, ATGP3510-1 mg, ATGP3510-10, ATGP3510-20, ATGP3510-50, ATGP3510-100, ATGP3510-250, ATGP3510-500, ATGP3510-1