Recombinant human VE-Cadherin/CDH5 protein

CDH5, as known as cadherin-5, is a member of the atypical/type 2 subgroup of Cadherin homophilic adhesion proteins. This protein plays a role in the formation, maturation and remodeling of the vascular wall. It is widely considered to be specific for vascular endothelia in which it is either the sole or the predominant cadherin, often co-existing with N-cadherin. Also, this protein regulates or is regulated by VEGF R2, type 1 and type 2 TGF-beta receptors, and other endothelial junction proteins such as JAM-C, Claudin-5, and N-Cadherin. Recombinant human CDH5, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Cadherin-5, CDH5, 7B4, CD144, Vascular endothelial cadherin

Expression System

Baculovirus

Antigen Species

Human

Tag

HIgG-His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Molecular Weight

91.5 kDa (810aa)

Additionnal Information

VE-Cadherin, Cadherin-5, CDH5, 7B4, CD144, ATGP3506-10 µg, ATGP3506-20 µg, ATGP3506-50 µg, ATGP3506-100 µg, ATGP3506-250 µg, ATGP3506-500 µg, ATGP3506-1 mg, ATGP3506-10, ATGP3506-20, ATGP3506-50, ATGP3506-100, ATGP3506-250, ATGP3506-500, ATGP3506-1