Recombinant human Chemerin protein
RARRES2, as known as retinoic acid receptor responder protein 2, is a distant member of the Cystatin superfamily. Members of this superfamily contain at least two intra-chain disulfide bonds and an alpha-helical structure over a distance of about 100 amino acids. This protein was found to stimulate chemotaxis of dendritic cells and macrophages to the site of inflammation. Also, it has been implicated in autocrine/paracrine signaling for adipocyte differentiation and also stimulation of lipolysis. Recombinant human RARRES2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Retinoic acid receptor responder protein 2, RARRES2, HP10433, TIG2, Chemerin
Expression System
Baculovirus
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 90% by SDS-PAGE
Molecular Weight
16.9 kDa (146aa)
Additionnal Information
References & Citations
Hatziagelaki E., et al, (2015) PLoS ONE 10:E0124935.; ; Zabel BA., et al, (2014) Am J Clin Exp Immunol. 3:1-19.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Cardiovascular
NCBI Accession Number
NP_002880
Uniprot Accession Number
Q99969
Species
Human
N Terminal Sequence
Ala
AA Sequence
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