Recombinant mouse Cathepsin D protein

Ctsd, also known as cathepsin D, is peptidase belonging to the family of aspartic peptidases. It is intracellular catabolism in lysosomal compartments, other physiological effect include hormone and antigen processing. It plays an important role in alpha-synuclein degradation, and neuronal survival. It has also been shown to mediate apoptosis induced by various stimuli and p53-dependent tumor suppression. Recombinant mouse Ctsd, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Specifications

Specific activity is > 1,000 pmol/min/ug in which one unit will convert 1.0 pmole of Mca-PLGL-Dpa-AR-NH2 to MCA- Pro-Leu-OH per minute at pH 3.5 at 25C.

Product Name Alternative

Cathepsin D, Ctsd, CatD, CD

Expression System

Baculovirus

Antigen Species

Mouse

Tag

His-Tag

Applications

Enzyme Activity, SDS-PAGE

Concentration

0.25 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Bioactivity

Specific activity is > 1,000pmol/min/ug in which one unit will convert 1.0pmole of Mca-PLGL-Dpa-AR-NH2 to MCA- Pro-Leu-OH per minute at pH 3.5 at 25C.

Molecular Weight

44 kDa (398aa)

Additionnal Information

Cathepsin D, Cathepsin D, Ctsd, CatD, CD, ATGP3490-10 µg, ATGP3490-20 µg, ATGP3490-50 µg, ATGP3490-100 µg, ATGP3490-250 µg, ATGP3490-500 µg, ATGP3490-1 mg, ATGP3490-10, ATGP3490-20, ATGP3490-50, ATGP3490-100, ATGP3490-250, ATGP3490-500, ATGP3490-1