Recombinant human t-Plasminogen Activator/PLAT protein

PLAT, as known as tissue-type plasminogen activator isoform 1, is a secreted serine protease synthesized by endothelial cells. This protein is secreted as a single chain polypeptide precursor which is cleaved in turn by plasmin. Also, it plays a role clinical medicine to treat stroke in cell migration and tissue remodeling. It is implicated in normal neural function and is suggested as a regulatory molecule in neurodegenerative diseases. Recombinant human PLAT, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Tissue-type plasminogen activator isoform 1, PLAT, T-PA, TPA

Expression System

Baculovirus

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Molecular Weight

61.3 kDa (545aa)

Additionnal Information

T-Plasminogen Activator, Tpa, Tissue-type plasminogen activator isoform 1, PLAT, T-PA, TPA, ATGP3486-10 µg, ATGP3486-20 µg, ATGP3486-50 µg, ATGP3486-100 µg, ATGP3486-250 µg, ATGP3486-500 µg, ATGP3486-1 mg, ATGP3486-10, ATGP3486-20, ATGP3486-50, ATGP3486-100, ATGP3486-250, ATGP3486-500, ATGP3486-1