Recombinant human CD68 protein

CD68, also known as macrosialin, is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. It is expressed on monocytes/macrophages. It is found in cytoplasmic granules and in the cytoplasm of various non-hematopoietic tissues including liver and kidney tubules and glomeruli. CD68 is also found on the surface of macrophages, monocytes, neutrophils, basophils and large lymphocytes. Recombinant human CD68 protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

SCARD1, Macrosialin isoform A, Macrosialin, LAMP4, GP110, CD68

Expression System

Baculovirus

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 95% by SDS-PAGE

Molecular Weight

32.6 kDa (307aa)

Additionnal Information

CD68, Macrosialin isoform A, CD68, GP110, LAMP4, SCARD1, ATGP3484-10 µg, ATGP3484-20 µg, ATGP3484-50 µg, ATGP3484-100 µg, ATGP3484-250 µg, ATGP3484-500 µg, ATGP3484-1 mg, ATGP3484-10, ATGP3484-20, ATGP3484-50, ATGP3484-100, ATGP3484-250, ATGP3484-500, ATGP3484-1

References & Citations

Strobl H. et al., (1995) Br. J. Haematol. 90:774-782.; ; Ogawa Y. et al., (1995) Pathol. Int. 45:698-701.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Scientific Category

Immunology

NCBI Accession Number

NP_001242

Uniprot Accession Number

P34810

Species

Human

N Terminal Sequence

Ala

AA Sequence

ADPNDCPHKK SATLLPSFTV TPTVTESTGT TSHRTTKSHK TTTHRTTTTG TTSHGPTTAT HNPTTTSHGN VTVHPTSNST ATSQGPSTAT HSPATTSHGN ATVHPTSNST ATSPGFTSSA HPEPPPPSPS PSPTSKETIG DYTWTNGSQP CVHLQAQIQI RVMYTTQGGG EAWGISVLNP NKTKVQGSCE GAHPHLLLSF PYGHLSFGFM QDLQQKVVYL SYMAVEYNVS FPHAAQWTFS AQNASLRDLQ APLGQSFSCS NSSIILSPAV HLDLLSLRLQ AAQLPHTGVF GQSFSCPSDR SHHHHHH