Recombinant human ADH1A protein
ADH1A, also known as alcohol dehydrogenase 1A, belongs to the alcohol dehydrogenase family. It plays a key role in hepatic alcohol catabolism. Its activity may be the cause of disorders in metabolic pathways that use these isoenzymes and could increase the concentration of acetaldehyde, which is cancerogenic substance. It is positively correlated with those of CDR1, CDR2 and FLU1. Recombinant human ADH1A, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Alcohol dehydrogenase 1A, ADH1A, ADH1
Expression System
Baculovirus
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 95% by SDS-PAGE
Molecular Weight
40.6 kDa (381aa)
Additionnal Information
References & Citations
Orywal K., et al. (2010) J Clin Lab Anal. 24:334-339.; ; Yasunami M., et al. (1990) Genomics. 7:152-158.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Signal Transduction
NCBI Accession Number
NP_000658
Uniprot Accession Number
P07327
Species
Human
N Terminal Sequence
Met1
AA Sequence
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